P-121 Factors associated with technical difficulty in colorectal endoscopic submucosal dissection

Colorectal endoscopic submucosal dissection (ESD) is not widely performed due to its technical difficulty. We aimed find the predictive factors of difficulty in colorectal ESD before procedure. Clinical data from patients who underwent for tumor five hospitals Honam province South Korea between 2015 2020 were reviewed retrospectively. Technically difficult was defined occuration perforation or failure en bloc resection and procedure time longer than 60 minutes. Factors associated with included as main outcome measure. Results: Total 1446 enrolled their clinical analyzed. procedures including long time(>60min) 398 cases (27.5%), occurred 34 (2.3%) en-bloc done 1292 (89.3%). Size larger 35mm (odd ratio [OR] 1.480, p=0.036), central depression lesion (OR 1.441, p=0.019), previous EMR polypectomy 2.498, p=0.016) technically ESD. Descending colon located 5.238, p < 0.001), use IT knife 4.564, p=0.002) perforation. 30mm 1.680, p=0.023), non-LST lesions 1.618, p=0.004), 2.512, p=0.025) time. Preoperative predictors should be considered identify gradient each neoplasm type appropriate setting